• Drug Discovery. Accelerated.

    IMPROVING HEALTH THROUGH COMPUTATION

  • twoXAR is an artificial intelligence-driven drug discovery company. The company leverages its computational platform to identify promising drug candidates, de-risks the opportunities through preclinical studies, and progresses drug candidates to the clinic through industry and investor partnerships.

  • ARTIFICIAL INTELLIGENCE-DRIVEN DRUG DISCOVERY

    The convergence of big data, cloud computing, and artificial intelligence has allowed twoXAR to build a drug discovery platform that is order of magnitudes faster, cheaper, and more accurate than traditional wet-lab based approaches.

     

    twoXAR leverages its technology internally to build its own pipeline of therapeutic candidates across diseases as well as collaborate with biotechnology and pharmaceutical companies to jointly discover and develop novel drug candidates by:​

    Screening compound libraries for efficacy against a disease or list of diseases

    Identifying new drug candidates from a public library for a disease that can be developed or used as a tool compound to elucidate novel biology & create new chemical entities

    Identifying biologic targets from the elucidation of novel biology

  • Andrew A. Radin, CEO - TEDMED 2016

  • COLLABORATING WITH US

    • Fast: typical engagement is from handshake to predictions in less than six months

    • Scalable: process data sets of any size in minutes using an elastic computing environment

    • Unbiased: predictions are based on statistical modeling

    • Comprehensive: leverages gene expression, protein-interaction, chemical structure, MOA, and clinical data, among others – it even handles noisy or incomplete assays

    • Agnostic: models work with any disease and have been tested on more than 80 diseases to date

  • Interested in collaborating with twoXAR to fill your drug pipeline?

  • PARTNERS

  • PUBLICATIONS & POSTERS

    Yen S Low, Aaron C Daugherty, Elizabeth A Schroeder, William Chen, Tina Seto, Susan Weber, Michael Lim, Trevor Hastie, Maya Mathur, Manisha Desai, Carl Farrington, Andrew A Radin, Marina Sirota, Pragati Kenkare, Caroline A Thompson, Peter P Yu, Scarlett L Gomez, George W Sledge Jr, Allison W Kurian, Nigam H Shah. Journal of the American Medical Informatics Association. EPub: December 9, 2016

     

    Poster: An Integrative Bioinformatics Approach Identifies In Vivo Validated Drug Candidates with Novel Mechanisms of Action in Rheumatoid Arthritis​

    Aaron C Daugherty1, Carl Farrington1, Isaac Hakim1, Elizabeth S Noblin1, Andrew M Radin1, Mei-Sze Chua2, Mark Rabe3, Guy Fernald3, Daniel Ford3, Marina Sirota4, Laura Schaevitz3, Andrew A Radin1

    1twoXAR, 2Stanford University School of Medicine, 3Vium, 4UCSF

    Download Poster (PDF)

    Download Supplementary Material (PDF)

     

  • MANAGEMENT

    The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. The co-founding team is from the Stanford School of Medicine and the MIT Sloan School of Management and was brought together by a common name (though not related) and a passion for entrepreneurship and technology.

    Andrew A. Radin

    CEO & Co-Founder

    Prior to co-founding twoXAR, Andrew held Chief Technology Officer roles at several early stage companies where he managed teams as large as a hundred technologists distributed around the world. Andrew developed the company's proprietary algorithm and as Chief Executive Officer is focused on overall company strategy, product development and fundraising. Andrew studied biomedical informatics in Stanford University's SCPD graduate program and holds Master of Science and Bachelor of Science degrees in computer science from Rochester Institute of Technology.

    Andrew M. Radin

    Chief Marketing Officer & Co-Founder

    Andrew M. Radin formerly worked as an investor in venture and private equity funds at Macquarie Bank and has designed, built, and managed several small organizations. Andrew co-founded a mobile platform startup while at MIT. As Chief Marketing Officer of twoXAR, Andrew is focused on understanding the market, identifying partners, and communicating the business. Andrew holds a Master in Business Administration degree from MIT Sloan, a Bachelor of Science degree in biochemistry and cell biology from UCSD, and a Bachelor of Arts degree in economics from UCSD.

    Brian Moriarty

    Chief Financial Officer

    Brian was formerly a VP at Hewlett-Packard leading the HR group responsible for M&A and outsourcing. He also was VP of M&A at Sun Microsystems where he led over 17 transactions. He also has experience as CFO of ChartONE, a healthcare service company. Brian holds a Master in Business Administration degree from Northwestern and a Bachelor of Arts degree in both English and economics from UC Davis.

    Jill Jene, PhD

    Senior Vice President, Business Development

    Jill has nearly 20 years of life science business development expertise with a deal sheet totaling over $3 Billion. Previously VP, Business Development at Depomed, she closed 20+ transactions and acquired 4 commercial franchises. Prior, she held business roles at Baxter, Cell Genesys (acquired by Biosante), and 3M Pharmaceutical Division (now Valeant). Jill holds a Bacheler of Science degree with honors in chemistry from Bradley University, both a PhD and Master of Science in chemistry from Northwestern University, and a Master in Business Administration degree from DePaul University.

  • SCIENTIFIC ADVISORY BOARD

    The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. We are a co-founding team from the Stanford School of Medicine and the MIT Sloan School of Management brought together by a common name (though not related) and a passion for entrepreneurship and technology.

    Vijay Pande, PhD

    Scientific Advisor

    Nigam Shah, MBBS, PhD

    Scientific Advisor

    Marina Sirota, PhD

    Scientific Advisor

  • CAREERS

    Interested in joining the twoXAR team?

     

    We are currently hiring: