• Drug Discovery. Accelerated.

    IMPROVING HEALTH THROUGH COMPUTATION

  • twoXAR is an artificial intelligence-driven drug discovery company. The company leverages its computational platform to identify promising drug candidates, de-risks the opportunities through preclinical studies, and progresses drug candidates to the clinic through industry and investor partnerships.

  • ARTIFICIAL INTELLIGENCE-DRIVEN DRUG DISCOVERY

    The convergence of big data, cloud computing, and artificial intelligence has allowed twoXAR to build a drug discovery platform that is order of magnitudes faster, cheaper, and more accurate than traditional wet-lab based approaches.

     

    twoXAR leverages its technology internally to build its own pipeline of therapeutic candidates across diseases as well as collaborate with biotechnology and pharmaceutical companies to jointly discover and develop novel drug candidates by:​

    Screening compound libraries for efficacy against a disease or list of diseases

    Identifying new drug candidates from a public library for a disease that can be developed or used as a tool compound to elucidate novel biology & create new chemical entities

    Identifying biologic targets from the elucidation of novel biology

  • Andrew A. Radin, CEO - TEDMED 2016

  • COLLABORATING WITH US

    • Fast: typical engagement is from handshake to predictions in less than six months

    • Scalable: process data sets of any size in minutes using an elastic computing environment

    • Unbiased: predictions are based on statistical modeling

    • Comprehensive: leverages gene expression, protein-interaction, chemical structure, MOA, and clinical data, among others – it even handles noisy or incomplete assays

    • Agnostic: models work with any disease and have been tested on more than 80 diseases to date

  • Interested in collaborating with twoXAR to fill your drug pipeline?

  • PARTNERS

  • PUBLICATIONS & POSTERS

    Yen S Low, Aaron C Daugherty, Elizabeth A Schroeder, William Chen, Tina Seto, Susan Weber, Michael Lim, Trevor Hastie, Maya Mathur, Manisha Desai, Carl Farrington, Andrew A Radin, Marina Sirota, Pragati Kenkare, Caroline A Thompson, Peter P Yu, Scarlett L Gomez, George W Sledge Jr, Allison W Kurian, Nigam H Shah. Journal of the American Medical Informatics Association. EPub: December 9, 2016

     

    Poster: An Integrative Bioinformatics Approach Identifies In Vivo Validated Drug Candidates with Novel Mechanisms of Action in Rheumatoid Arthritis​

    Aaron C Daugherty1, Carl Farrington1, Isaac Hakim1, Elizabeth S Noblin1, Andrew M Radin1, Mei-Sze Chua2, Mark Rabe3, Guy Fernald3, Daniel Ford3, Marina Sirota4, Laura Schaevitz3, Andrew A Radin1

    1twoXAR, 2Stanford University School of Medicine, 3Vium, 4UCSF

    Download Poster (PDF)

    Download Supplementary Material (PDF)

     

  • MANAGEMENT

    The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. We are a co-founding team from the Stanford School of Medicine and the MIT Sloan School of Management brought together by a common name (though not related) and a passion for entrepreneurship and technology.

    Andrew A. Radin

    CEO & Co-Founder

    Andrew led technology teams as CTO at three startups prior to twoXAR, and led technical diligence for Vanedge Capital. An acquisition by Apple Computer allowed him to return to school to study Biomedical Informatics at Stanford University which led to the founding of twoXAR. Andrew holds a BS and MS degrees in CS from Rochester Institute of Technology.

     

    Andrew M. Radin

    Chief Marketing Officer & Co-Founder

    Andrew formerly worked as an investor in venture and private equity funds. While at MIT, Andrew co-founded a mobile platform startup. Andrew holds an MBA degree from MIT Sloan, a BS degree in Biochemistry and Cell Biology from UCSD, and a BA degree in Economics.

  • SCIENTIFIC ADVISORY BOARD

    The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. We are a co-founding team from the Stanford School of Medicine and the MIT Sloan School of Management brought together by a common name (though not related) and a passion for entrepreneurship and technology.

    Vijay Pande, PhD

    Scientific Advisor

    Nigam Shah, MBBS, PhD

    Scientific Advisor

    Marina Sirota, PhD

    Scientific Advisor

  • CAREERS

    Interested in joining the twoXAR team?

     

    We are currently hiring: