Drug Discovery. Accelerated.
IMPROVING HEALTH THROUGH COMPUTATION
twoXAR is an artificial intelligence-driven drug discovery company. The company leverages its computational platform to identify promising drug candidates, de-risks the opportunities through preclinical studies, and progresses drug candidates to the clinic through industry and investor partnerships.
Andrew A. Radin, CEO - TEDMED 2016
COLLABORATING WITH US
Fast: typical engagement is from handshake to predictions in less than six months
Scalable: process data sets of any size in minutes using an elastic computing environment
Unbiased: predictions are based on statistical modeling
Comprehensive: leverages gene expression, protein-interaction, chemical structure, MOA, and clinical data, among others – it even handles noisy or incomplete assays
Agnostic: models work with any disease and have been tested on more than 80 diseases to date
PUBLICATIONS & POSTERS
Yen S Low, Aaron C Daugherty, Elizabeth A Schroeder, William Chen, Tina Seto, Susan Weber, Michael Lim, Trevor Hastie, Maya Mathur, Manisha Desai, Carl Farrington, Andrew A Radin, Marina Sirota, Pragati Kenkare, Caroline A Thompson, Peter P Yu, Scarlett L Gomez, George W Sledge Jr, Allison W Kurian, Nigam H Shah. Journal of the American Medical Informatics Association. EPub: December 9, 2016
Poster: An Integrative Bioinformatics Approach Identifies In Vivo Validated Drug Candidates with Novel Mechanisms of Action in Rheumatoid Arthritis
Aaron C Daugherty1, Carl Farrington1, Isaac Hakim1, Elizabeth S Noblin1, Andrew M Radin1, Mei-Sze Chua2, Mark Rabe3, Guy Fernald3, Daniel Ford3, Marina Sirota4, Laura Schaevitz3, Andrew A Radin1
1twoXAR, 2Stanford University School of Medicine, 3Vium, 4UCSF
The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. The co-founding team is from the Stanford School of Medicine and the MIT Sloan School of Management and was brought together by a common name (though not related) and a passion for entrepreneurship and technology.
Andrew A. Radin
CEO & Co-Founder
Prior to co-founding twoXAR, Andrew held Chief Technology Officer roles at several early stage companies where he managed teams as large as a hundred technologists distributed around the world. Andrew developed the company's proprietary algorithm and as Chief Executive Officer is focused on overall company strategy, product development and fundraising. Andrew studied biomedical informatics in Stanford University's SCPD graduate program and holds Master of Science and Bachelor of Science degrees in computer science from Rochester Institute of Technology.
Andrew M. Radin
Chief Marketing Officer & Co-Founder
Andrew M. Radin formerly worked as an investor in venture and private equity funds at Macquarie Bank and has designed, built, and managed several small organizations. Andrew co-founded a mobile platform startup while at MIT. As Chief Marketing Officer of twoXAR, Andrew is focused on understanding the market, identifying partners, and communicating the business. Andrew holds a Master in Business Administration degree from MIT Sloan, a Bachelor of Science degree in biochemistry and cell biology from UCSD, and a Bachelor of Arts degree in economics from UCSD.
Chief Financial Officer
Brian was formerly a VP at Hewlett-Packard leading the HR group responsible for M&A and outsourcing. He also was VP of M&A at Sun Microsystems where he led over 17 transactions. He also has experience as CFO of ChartONE, a healthcare service company. Brian holds a Master in Business Administration degree from Northwestern and a Bachelor of Arts degree in both English and economics from UC Davis.
Jill Jene, PhD
Senior Vice President, Business Development
Jill has nearly 20 years of life science business development expertise with a deal sheet totaling over $3 Billion. Previously VP, Business Development at Depomed, she closed 20+ transactions and acquired 4 commercial franchises. Prior, she held business roles at Baxter, Cell Genesys (acquired by Biosante), and 3M Pharmaceutical Division (now Valeant). Jill holds a Bacheler of Science degree with honors in chemistry from Bradley University, both a PhD and Master of Science in chemistry from Northwestern University, and a Master in Business Administration degree from DePaul University.
SCIENTIFIC ADVISORY BOARD
The twoXAR team is dedicated to improving health on a global scale by building a profit-generating business utilizing artificial intelligence. We are a co-founding team from the Stanford School of Medicine and the MIT Sloan School of Management brought together by a common name (though not related) and a passion for entrepreneurship and technology.
Vijay Pande, PhD
Nigam Shah, MBBS, PhD
Marina Sirota, PhD